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| Cat.No | ACP16390 | Target Name | PARS2 |
|---|---|---|---|
| Target Synonyms | PARS2; Probable proline--tRNA ligase; mitochondrial; EC 6.1.1.15; Prolyl-tRNA synthetase; ProRS | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 30-475 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7L3T8 |
|---|
Uniprot Id
Q7L3T8
Target Species
Human
Target Name
PARS2
Target Full Name
Probable proline--tRNA ligase, mitochondrial
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-II aminoacyl-tRNA synthetase family
Target Synonyms
PARS2; Probable proline--tRNA ligase; mitochondrial; EC 6.1.1.15; Prolyl-tRNA synthetase; ProRS
Target Background
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of proline to tRNA molecules. Mutations have been found in this gene in some patients with Alpers syndrome.
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