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| Cat.No | ACP10657 | Target Name | OSGEPL1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 30-414 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H4B0 |
|---|
Uniprot Id
Q9H4B0
Target Species
Human
Target Name
OSGEPL1
Target Full Name
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial
Target Function
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
Target Subcellular Location
Mitochondrion.
Target Protein Families
KAE1 / TsaD family
Target Tissue Specificity
Widely expressed, with maximum expression in pituitary gland, prostate, rectum and uterus.
Target Synonyms
O sialoglycoprotein endopeptidase like 1 ; O sialoglycoprotein endopeptidase like protein 1; osgepl1; OSGP2_HUMAN; Probable O sialoglycoprotein endopeptidase 2; Probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1; Putative sialoglycoprotease type 2; Qri7; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1
Target Background
Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Located in mitochondrion.
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