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| Cat.No | ACP18216 | Target Name | PDCD2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-344 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q16342 |
|---|
Uniprot Id
Q16342
Target Species
Human
Target Name
PDCD2
Target Full Name
Programmed cell death protein 2
Target Function
May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Ubiquitous.
Target Research Area
Cell Biology
Target Synonyms
MGC12347; OTTHUMP00000017702; PDCD 2; Pdcd2; PDCD2 protein; PDCD2_HUMAN; Programmed cell death 2; Programmed cell death protein 2; RP 8; RP8; Rp8 homolog; Zinc finger MYND domain containing protein 7; Zinc finger MYND domain-containing protein 7; Zinc finger protein Rp 8; Zinc finger protein Rp-8; Zinc finger protein Rp8; ZMYND 7; ZMYND7
Target Background
This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.
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