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| Cat.No | ACP11613 | Target Name | PRR14 |
|---|---|---|---|
| Target Synonyms | PRR14; Proline-rich protein 14 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-585 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BWN1 |
|---|
Uniprot Id
Q9BWN1
Target Species
Human
Target Name
PRR14
Target Full Name
Proline-rich protein 14
Target Function
Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha. Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit. Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha. Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2.
Target Subcellular Location
Chromosome. Nucleus. Nucleus lamina. Nucleus, nucleoplasm.
Target Synonyms
PRR14; Proline-rich protein 14
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