Recombinant Human Prolyl 4-hydroxylase subunit alpha-3 (P4HA3)

Cat.No	ACP15524	Target Name	P4HA3
Target Synonyms	2-oxoglutarate 4-dioxygenase, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), 2-oxoglutarate-4-dioxygenase subunit alpha-3; 4-PH alpha-3; P4ha3; P4HA3_HUMAN; Procollagen-proline; Procollagen-proline, 2-oxoglutarate-4-dioxygenase subunit alpha-3; Prolyl 4-hydroxylase subunit alpha-3; Prolyl 4-hydroxylase, alpha polypeptide III; Procollagen-proline, alpha polypeptide III; Prolyl 4-hydroxylase, alpha subunit, alpha-3 subunit, isoform 3; Procollagen-proline	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	20-544
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP15524

Target Name

P4HA3

Target Synonyms

2-oxoglutarate 4-dioxygenase, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), 2-oxoglutarate-4-dioxygenase subunit alpha-3; 4-PH alpha-3; P4ha3; P4HA3_HUMAN; Procollagen-proline; Procollagen-proline, 2-oxoglutarate-4-dioxygenase subunit alpha-3; Prolyl 4-hydroxylase subunit alpha-3; Prolyl 4-hydroxylase, alpha polypeptide III; Procollagen-proline, alpha polypeptide III; Prolyl 4-hydroxylase, alpha subunit, alpha-3 subunit, isoform 3; Procollagen-proline

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

20-544

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q7Z4N8

Background Information

Uniprot Id

Q7Z4N8
Target Species

Human
Target Name

P4HA3
Target Full Name

Prolyl 4-hydroxylase subunit alpha-3
Target Function

Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Target Subcellular Location

Endoplasmic reticulum lumen.
Target Protein Families

P4HA family
Target Tissue Specificity

Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions.
Target Research Area

Signal Transduction
Target Synonyms

2-oxoglutarate-4-dioxygenase subunit alpha-3; 4-PH alpha-3; P4ha3; P4HA3_HUMAN; Procollagen-proline; Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III; Procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha subunit, isoform 3; Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3; Prolyl 4-hydroxylase subunit alpha-3; Prolyl 4-hydroxylase, alpha polypeptide III; Prolyl 4-hydroxylase, alpha-3 subunit
Target Background

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternative splicing results in multiple transcript variants.

Recombinant Human Prolyl 4-hydroxylase subunit alpha-3 (P4HA3)

Specifications

Immunogen Information

Inquire Recombinant Human Prolyl 4-hydroxylase subunit alpha-3 (P4HA3) Now

Related Products