Recombinant Human Proprotein convertase subtilisin/kexin type 6 (PCSK6), Truncated

Cat.No	ACP00761	Target Name	PCSK6
Form	Liquid or Lyophilized powder	Expression System	E.coli
Expression Range	860-969aa	Mol Weight	19.4 kDa
Protein Length	Partial	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP00761

Target Name

PCSK6

Form

Liquid or Lyophilized powder

Expression System

E.coli

Expression Range

860-969aa

Mol Weight

19.4 kDa

Protein Length

Partial

Purity

Greater than 90% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P29122

Background Information

Uniprot Id

P29122
Target Species

Human
Target Name

PCSK6
Target Full Name

Proprotein convertase subtilisin/kexin type 6
Target Function

Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues.
Target Subcellular Location

[Isoform PACE4A-I]: Secreted.; [Isoform PACE4A-II]: Secreted.; [Isoform PACE4C]: Endoplasmic reticulum. Note=Not secreted, remains probably in zymogen form in endoplasmic reticulum.; [Isoform PACE4CS]: Endoplasmic reticulum. Note=Not secreted, remains probably in zymogen form in endoplasmic reticulum.; [Isoform PACE4E-I]: Endomembrane system; Peripheral membrane protein. Note=Retained intracellularly probably through a hydrophobic cluster in their C-terminus.; [Isoform PACE4E-II]: Endomembrane system; Peripheral membrane protein. Note=Retained intracellularly probably through a hydrophobic cluster in their C-terminus.; [Isoform PACE4B]: Secreted.
Target Protein Families

Peptidase S8 family
Target Tissue Specificity

Each PACE4 isoform exhibits a unique restricted distribution. Isoform PACE4A-I is expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, but at comparatively higher levels in the liver. Isoform PACE4A-II is at least expressed in pla
Target Research Area

Neuroscience
Target Synonyms

Paired basic amino acid cleaving enzyme 4; Paired basic amino acid cleaving system 4; PCSK6; PCSK6_HUMAN; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin like protease; Subtilisin-like proprotein convertase 4; subtilisin/kexin like protease PACE4; Subtilisin/kexin-like protease PACE4

Recombinant Human Proprotein convertase subtilisin/kexin type 6 (PCSK6), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Proprotein convertase subtilisin/kexin type 6 (PCSK6), Truncated Now

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