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| Cat.No | ACP12233 | Target Name | BEX1 |
|---|---|---|---|
| Target Synonyms | BEX1Protein BEX1; Brain-expressed X-linked protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-125 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HBH7 |
|---|
Uniprot Id
Q9HBH7
Target Species
Human
Target Name
BEX1
Target Full Name
Protein BEX1
Target Function
Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
BEX family
Target Tissue Specificity
Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia.
Target Synonyms
BEX1Protein BEX1; Brain-expressed X-linked protein 1
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