Recombinant Human Protein canopy homolog 3 (CNPY3)

Uniprot Id

Q9BT09

Target Species

Human

Target Name

CNPY3

Target Full Name

Protein canopy homolog 3

Target Function

Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses.

Target Subcellular Location

Endoplasmic reticulum.

Target Protein Families

Canopy family

Target Synonyms

CAG repeat containing; CAG4A; Canopy 3 homolog; cnpy3; CNPY3_HUMAN; CTG repeat protein 4a; ERDA 5; ERDA5; Expanded repeat domain CAG/CTG 5; Expanded repeat-domain protein CAG/CTG 5; OTTHUMP00000016408; PRAT4A; Protein associated with Tlr4; Protein associated with Toll like receptor 4A; Protein canopy homolog 3; TNRC 5; Trinucleotide repeat containing 5; Trinucleotide repeat-containing gene 5 protein

Target Background

This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644.