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| Cat.No | ACP05852 | Target Name | CIP2A |
|---|---|---|---|
| Target Synonyms | Cancerous inhibitor of PP2A; Cancerous Inhibitor of Protein Phosphatase 2A; CIP2A; CIP2A_HUMAN; FLJ12850; Kiaa1524; MGC163436; p90; p90 autoantigen; Protein CIP2A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TCG1 |
|---|
Uniprot Id
Q8TCG1
Target Species
Human
Target Name
CIP2A
Target Full Name
Protein CIP2A
Target Function
Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.
Target Subcellular Location
Membrane; Single-pass membrane protein. Cytoplasm.
Target Tissue Specificity
Expressed at low levels in most of the tissues. Overexpressed in head-and-neck squamous cell carcinomas (HNSCC). Present in liver cancer cells (at protein level).
Target Synonyms
Cancerous inhibitor of PP2A; Cancerous Inhibitor of Protein Phosphatase 2A; CIP2A; CIP2A_HUMAN; FLJ12850; Kiaa1524; MGC163436; p90; p90 autoantigen; Protein CIP2A
Target Background
Enables protein homodimerization activity. Predicted to act upstream of or within positive regulation of neural precursor cell proliferation and spermatogenesis. Located in cytosol and plasma membrane.
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