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Recombinant Human Protein DBF4 homolog A (DBF4)

ACP10494

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Specifications

Cat.No	ACP10494	Target Name	DBF4
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-674	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9UBU7

Background Information

Uniprot Id

Q9UBU7
Target Species

Human
Target Name

DBF4
Target Full Name

Protein DBF4 homolog A
Target Function

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Target Subcellular Location

Nucleus.
Target Tissue Specificity

Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
Target Synonyms

Activator of S phase kinase; ASK; CHIF; Chiffon homolog A; DBF4; DBF4 homolog (S. cerevisiae); DBF4 homolog; DBF4 type zinc finger containing protein 1; DBF4 zinc finger A; DBF4 zinc finger; DBF4; S. cerevisiae; homolog of; DBF4-type zinc finger-containing protein 1; DBF4A; DBF4A_HUMAN; Dumbbell former 4; S. cerevisiae; homolog of; OTTHUMP00000161661; Protein DBF4 homolog A; ZDBF1; Zinc finger; DBF-type containing 1
Target Background

Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Located in nuclear body.

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Recombinant Human Protein DBF4 homolog A (DBF4)

Specifications

Immunogen Information

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