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This Recombinant Human Protein Delta Homolog 1 (DLK1) is a valuable addition to your neuroscience research toolbox. DLK1, also known as DLK-1 or pG2, is a transmembrane protein that plays a crucial role in the development and differentiation of various cell types, particularly in the nervous system. Studies have implicated DLK1 in numerous biological processes, including neurogenesis, adipogenesis, and cell fate determination. Our Recombinant Human DLK1 protein is produced in a mammalian cell system, ensuring proper folding and post-translational modifications. The protein consists of a partial sequence (24-303aa) and is fused with a C-terminal Flag-Myc tag for efficient purification and detection. With a purity of greater than 90% as determined by SDS-PAGE, our DLK1 protein guarantees consistent performance in your experiments. Available in both liquid and lyophilized powder forms, this high-quality protein is designed to meet the diverse demands of your neuroscience research.
This Recombinant Human Protein Delta Homolog 1 (DLK1) is a valuable addition to your neuroscience research toolbox. DLK1, also known as DLK-1 or pG2, is a transmembrane protein that plays a crucial role in the development and differentiation of various cell types, particularly in the nervous system. Studies have implicated DLK1 in numerous biological processes, including neurogenesis, adipogenesis, and cell fate determination.
Our Recombinant Human DLK1 protein is produced in a mammalian cell system, ensuring proper folding and post-translational modifications. The protein consists of a partial sequence (24-303aa) and is fused with a C-terminal Flag-Myc tag for efficient purification and detection. With a purity of greater than 90% as determined by SDS-PAGE, our DLK1 protein guarantees consistent performance in your experiments. Available in both liquid and lyophilized powder forms, this high-quality protein is designed to meet the diverse demands of your neuroscience research.
| Cat.No | ACP02792 | Target Name | DLK1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | Mammalian cell |
| Expression Range | 24-303aa | Mol Weight | 32.8 kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P80370 |
|---|
Uniprot Id
P80370
Target Species
Human
Target Name
DLK1
Target Full Name
Protein delta homolog 1
Target Function
May have a role in neuroendocrine differentiation.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Cytoplasm.
Target Tissue Specificity
Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendo
Target Research Area
Neuroscience
Target Synonyms
Adipocyte differentiation inhibitor protein; Brevideltin; Delta like 1 homolog; Delta like homolog; Delta like protein; Delta1; DLK 1; DLK; DLK-1; DLK1; DLK1_HUMAN; FA 1; FA1; Fetal antigen 1; pG2; Preadipocyte factor 1; Pref 1; Pref; Pref1; Protein delta homolog 1; Secredeltin; ZOG
Target Background
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
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