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| Cat.No | ACP12686 | Target Name | FAM168A |
|---|---|---|---|
| Target Synonyms | F168A_HUMAN; Fam168a; KIAA0280; Protein FAM168A; TCRP1; Tongue cancer chemotherapy resistance-associated protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-244 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92567 |
|---|
Uniprot Id
Q92567
Target Species
Human
Target Name
FAM168A
Target Full Name
Protein FAM168A
Target Function
In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels.
Target Involvement
Associated with cisplatin (DDP)-resistance and radioresistance in the treatment of lung cancer as well as oral squamous cell carcinoma and poor clinical outcome in patients.
Target Protein Families
FAM168 family
Target Synonyms
F168A_HUMAN; Fam168a; KIAA0280; Protein FAM168A; TCRP1; Tongue cancer chemotherapy resistance-associated protein 1
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