Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP19790 | Target Name | MCRIP1 |
|---|---|---|---|
| Target Synonyms | MCRIP1; FAM195B; GRAN2; Mapk-regulated corepressor-interacting protein 1; Granulin-2; Protein FAM195B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-97 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | C9JLW8 |
|---|
Uniprot Id
C9JLW8
Target Species
Human
Target Name
MCRIP1
Target Full Name
Mapk-regulated corepressor-interacting protein 1
Target Function
The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition.
Target Subcellular Location
Nucleus. Cytoplasm, Stress granule.
Target Protein Families
MCRIP family
Target Synonyms
MCRIP1; FAM195B; GRAN2; Mapk-regulated corepressor-interacting protein 1; Granulin-2; Protein FAM195B
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
