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Recombinant Human Protein lin-54 homolog (LIN54)

ACP16581

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16581 Target NameLIN54
Target SynonymsCXC domain containing 1; CXC domain-containing protein 1; CXCDC1; JC8.6; Kiaa2037; lin-54 homolog (C. elegans); Lin54; LIN54_HUMAN; MIP120; Protein lin-54 homolog; protein lin54 homologFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-749
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6MZP7
Background Information
  • Uniprot Id

    Q6MZP7

  • Target Species

    Human

  • Target Name

    LIN54

  • Target Full Name

    Protein lin-54 homolog

  • Target Function

    Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Lin-54 family

  • Target Synonyms

    CXC domain containing 1; CXC domain-containing protein 1; CXCDC1; JC8.6; Kiaa2037; lin-54 homolog (C. elegans); Lin54; LIN54_HUMAN; MIP120; Protein lin-54 homolog; protein lin54 homolog

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