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| Cat.No | ACP16581 | Target Name | LIN54 |
|---|---|---|---|
| Target Synonyms | CXC domain containing 1; CXC domain-containing protein 1; CXCDC1; JC8.6; Kiaa2037; lin-54 homolog (C. elegans); Lin54; LIN54_HUMAN; MIP120; Protein lin-54 homolog; protein lin54 homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-749 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6MZP7 |
|---|
Uniprot Id
Q6MZP7
Target Species
Human
Target Name
LIN54
Target Full Name
Protein lin-54 homolog
Target Function
Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA
Target Subcellular Location
Nucleus.
Target Protein Families
Lin-54 family
Target Synonyms
CXC domain containing 1; CXC domain-containing protein 1; CXCDC1; JC8.6; Kiaa2037; lin-54 homolog (C. elegans); Lin54; LIN54_HUMAN; MIP120; Protein lin-54 homolog; protein lin54 homolog
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