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Recombinant Human Protein NPAT (NPAT), Truncated

ACP17955

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Specifications

Cat.No	ACP17955	Target Name	NPAT
Target Synonyms	NPAT; CAND3; E14; Protein NPAT; Nuclear protein of the ataxia telangiectasia mutated locus; Nuclear protein of the ATM locus; p220	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q14207

Background Information

Uniprot Id

Q14207
Target Species

Human
Target Name

NPAT
Target Full Name

Protein NPAT
Target Function

Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.
Target Subcellular Location

Nucleus. Nucleus, Cajal body. Note=Concentrates in two Cajal bodies tethered to histone gene clusters at chromosome 6p21 during G1, S and G2 phases. Also concentrates in two additional Cajal bodies tethered to histone gene clusters at chromosome 1q21 specifically during S and G2 phases.
Target Protein Families

NPAT family
Target Tissue Specificity

Ubiquitously expressed.
Target Synonyms

NPAT; CAND3; E14; Protein NPAT; Nuclear protein of the ataxia telangiectasia mutated locus; Nuclear protein of the ATM locus; p220

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Recombinant Human Protein NPAT (NPAT), Truncated

Specifications

Immunogen Information

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