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| Cat.No | ACP11559 | Target Name | SMG9 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-520 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H0W8 |
|---|
Uniprot Id
Q9H0W8
Target Species
Human
Target Name
SMG9
Target Full Name
Nonsense-mediated mRNA decay factor SMG9
Target Function
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8. Plays a role in brain, heart, and eye development.
Target Involvement
Heart and brain malformation syndrome (HBMS)
Target Protein Families
SMG9 family
Target Synonyms
C19orf61; Chromosome 19 open reading frame 61; DKFZp564H1322; F17127_1; FLJ12886; Protein smg 9 homolog; Protein smg-9 homolog; Protein SMG9; SMG 9; smg9; SMG9_HUMAN; Suppressor with morphogenetic effect on genitalia protein 9,
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