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| Cat.No | ACP21295 | Target Name | SOX15 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-233 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O60248 |
|---|
Uniprot Id
O60248
Target Species
Human
Target Name
SOX15
Target Full Name
Transcription factor SOX-15
Target Function
Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence. Acts as a transcriptional activator and repressor. Binds synergistically with POU5F1 (OCT3/4) to gene promoters. Binds to the FOXK1 promoter and recruits FHL3, resulting in transcriptional activation of FOXK1 which leads to myoblast proliferation. Acts as an inhibitor of myoblast differentiation via transcriptional repression which leads to down-regulation of the muscle-specific genes MYOD and MYOG. Involved in trophoblast giant cell differentiation via enhancement of HAND1 transcriptional activity. Regulates transcription of HRC via binding to it proximal enhancer region. Involved in skeletal muscle regeneration. Also plays a role in the development of myogenic precursor cells
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.
Target Synonyms
Protein SOX-12; Protein SOX-15; Protein SOX-20; SOX 12 protein ; SOX 15; SOX 15 protein; SOX 20 protein; SOX12; SOX12 protein ; SOX15; SOX15 protein; SOX15_HUMAN; SOX20; SOX20 protein; SOX26; SOX27; SRY box 15; SRY sex determining region Y box 15; SRY sex determining region Y box 20 ; SRYbox 15
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