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| Cat.No | ACP16920 | Target Name | SPTY2D1 |
|---|---|---|---|
| Target Synonyms | SPTY2D1; Protein SPT2 homolog; Protein KU002155; SPT2 domain-containing protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-685 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q68D10 |
|---|
Uniprot Id
Q68D10
Target Species
Human
Target Name
SPTY2D1
Target Full Name
Protein SPT2 homolog
Target Function
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription. Binds DNA and histones and promotes nucleosome assembly (in vitro). Facilitates formation of tetrameric histone complexes containing histone H3 and H4. Modulates RNA polymerase 1-mediated transcription. Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
SPT2 family
Target Synonyms
SPTY2D1; Protein SPT2 homolog; Protein KU002155; SPT2 domain-containing protein 1
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