Recombinant Human Protein Wnt-3a (WNT3A), Truncated

WNT3A protein CSB-EP026136HU1 is a recombinant human partial-length protein produced in E.coli. A DNA sequence encoding 19-351aa of human WNT3A protein was fused with an N-terminal 6xHis-tag and then contained within the protein. The purity of this WNT3A protein is greater than 90% as determined by SDS-PAGE. And it was elevated in the LC-MS/MS Analysis. CUSABIO provides in-stock WNT3A proteins and reduces the time for the products to reach the laboratory table. WNT3A is a member of canonical WNT ligand and modulates different pleiotropic cellular functions such as self-renewal, proliferation, differentiation, and motility. It is closely related to the etiology and pathology of numerous diseases including cancer. Depending on cancer type, WNT3A augments or inhibits metastasis, cell proliferation, and apoptosis of cancer cells.

ACP02274

WNT3A protein CSB-EP026136HU1 is a recombinant human partial-length protein produced in E.coli. A DNA sequence encoding 19-351aa of human WNT3A protein was fused with an N-terminal 6xHis-tag and then contained within the protein. The purity of this WNT3A protein is greater than 90% as determined by SDS-PAGE. And it was elevated in the LC-MS/MS Analysis. CUSABIO provides in-stock WNT3A proteins and reduces the time for the products to reach the laboratory table.
WNT3A is a member of canonical WNT ligand and modulates different pleiotropic cellular functions such as self-renewal, proliferation, differentiation, and motility. It is closely related to the etiology and pathology of numerous diseases including cancer. Depending on cancer type, WNT3A augments or inhibits metastasis, cell proliferation, and apoptosis of cancer cells.

Number

Cat.No	ACP02274	Target Name	WNT3A
Target Synonyms	Protein Wnt 3a Precursor; Protein Wnt-3a; Wingless type MMTV integration site family member 3A; Wnt 3a; wnt3a; WNT3A protein; WNT3A_HUMAN	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	19-351aa
Mol Weight	41.3kDa	Protein Length	Partial
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP02274

Target Name

WNT3A

Target Synonyms

Protein Wnt 3a Precursor; Protein Wnt-3a; Wingless type MMTV integration site family member 3A; Wnt 3a; wnt3a; WNT3A protein; WNT3A_HUMAN

Form

Liquid or Lyophilized powder

Expression System

E.coli

Expression Range

19-351aa

Mol Weight

41.3kDa

Protein Length

Partial

Purity

Greater than 90% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P56704

Background Information

Uniprot Id

P56704
Target Species

Human
Target Name

WNT3A
Target Full Name

Protein Wnt-3a
Target Function

Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube. Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro).
Target Subcellular Location

Secreted, extracellular space, extracellular matrix. Secreted.
Target Protein Families

Wnt family
Target Tissue Specificity

Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate.
Target Research Area

Developmental Biology, Signal Transduction
Target Synonyms

Protein Wnt 3a Precursor; Protein Wnt-3a; Wingless type MMTV integration site family member 3A; Wnt 3a; wnt3a; WNT3A protein; WNT3A_HUMAN
Target Background

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.

Recombinant Human Protein Wnt-3a (WNT3A), Truncated

Specifications

Immunogen Information

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