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| Cat.No | ACP18840 | Target Name | PRG3 |
|---|---|---|---|
| Target Synonyms | PRG3; MBPH; UNQ486/PRO1002Proteoglycan 3; Eosinophil major basic protein homolog; Prepro-major basic protein homolog; Prepro-MBPH | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 18-225 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y2Y8 |
|---|
Uniprot Id
Q9Y2Y8
Target Species
Human
Target Name
PRG3
Target Full Name
Proteoglycan 3
Target Function
Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.
Target Subcellular Location
Cytoplasmic granule. Note=Localized to the eosinophil secondary granule.
Target Tissue Specificity
Expressed in bone marrow. Not detected in placenta.
Target Synonyms
PRG3; MBPH; UNQ486/PRO1002Proteoglycan 3; Eosinophil major basic protein homolog; Prepro-major basic protein homolog; Prepro-MBPH
Target Background
An extracellular matrix structural constituent conferring compression resistance. Involved in several processes, including granulocyte activation; histamine biosynthetic process; and regulation of gene expression. Located in collagen-containing extracellular matrix.
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