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| Cat.No | ACP20676 | Target Name | PCDH8 |
|---|---|---|---|
| Target Synonyms | PCDH8Protocadherin-8; Arcadlin | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95206 |
|---|
Uniprot Id
O95206
Target Species
Human
Target Name
PCDH8
Target Full Name
Protocadherin-8
Target Function
Calcium-dependent cell-adhesion protein. May play a role in activity-induced synaptic reorganization underlying long term memory. Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane.
Target Synonyms
PCDH8Protocadherin-8; Arcadlin
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