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| Cat.No | ACP16538 | Target Name | FAT4 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6V0I7 |
|---|
Uniprot Id
Q6V0I7
Target Species
Human
Target Name
FAT4
Target Full Name
Protocadherin Fat 4
Target Function
Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation.
Target Involvement
Van Maldergem syndrome 2 (VMLDS2); Hennekam lymphangiectasia-lymphedema syndrome 2 (HKLLS2)
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer.
Target Synonyms
Cadherin family member 14; Cadherin related family member 11; CDHF14; CDHR11; FAT atypical cadherin 4; FAT J; FAT tumor suppressor homolog 4; Fat-like cadherin protein FAT-J; FAT4; FAT4_HUMAN; FATJ; hFat4; HKLLS2; Nbla00548; Protocadherin Fat 4; Putative protein product of Nbla00548; VMLDS2
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