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| Cat.No | ACP12145 | Target Name | ASXL3 |
|---|---|---|---|
| Target Synonyms | ASXL3; KIAA1713; Putative Polycomb group protein ASXL3; Additional sex combs-like protein 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9C0F0 |
|---|
Uniprot Id
Q9C0F0
Target Species
Human
Target Name
ASXL3
Target Full Name
Putative Polycomb group protein ASXL3
Target Function
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility.
Target Involvement
Bainbridge-Ropers syndrome (BRPS)
Target Subcellular Location
Nucleus.
Target Protein Families
Asx family
Target Tissue Specificity
Expressed in pancreatic islets, testis, neuroblastoma, head and neck tumor.
Target Synonyms
ASXL3; KIAA1713; Putative Polycomb group protein ASXL3; Additional sex combs-like protein 3
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