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| Cat.No | ACP13393 | Target Name | TOP6BL |
|---|---|---|---|
| Target Synonyms | C11orf80; Chromosome 11 open reading frame 80; CK080_HUMAN; Putative uncharacterized protein C11orf80; Uncharacterized protein C11orf80 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 24-677 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N6T0 |
|---|
Uniprot Id
Q8N6T0
Target Species
Human
Target Name
TOP6BL
Target Full Name
Type 2 DNA topoisomerase 6 subunit B-like
Target Function
Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.
Target Subcellular Location
Chromosome.
Target Protein Families
TOP6B-like family
Target Tissue Specificity
Detected in lung, spleen,colon and in skeletal muscle. Expressed in the ovaries, Fallopian tubes and uterus.
Target Synonyms
C11orf80; Chromosome 11 open reading frame 80; CK080_HUMAN; Putative uncharacterized protein C11orf80; Uncharacterized protein C11orf80
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