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| Cat.No | ACP17283 | Target Name | PYDC2 |
|---|---|---|---|
| Target Synonyms | PYDC2; POP2; Pyrin domain-containing protein 2; Pyrin-only protein 2; cellular POP2; cPOP2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-97 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q56P42 |
|---|
Uniprot Id
Q56P42
Target Species
Human
Target Name
PYDC2
Target Full Name
Pyrin domain-containing protein 2
Target Function
May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome. May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Tissue Specificity
Predominantly expressed in peripheral blood. Weakly expressed in testis.
Target Synonyms
PYDC2; POP2; Pyrin domain-containing protein 2; Pyrin-only protein 2; cellular POP2; cPOP2
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