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Recombinant Human Rab11 family-interacting protein 3 (RAB11FIP3)

ACP20742

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20742 Target NameRAB11FIP3
Target SynonymsRAB11FIP3; ARFO1; KIAA0665; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3; Arfophilin-1; EF hands-containing Rab-interacting protein; Eferin; MU-MB-17.148FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-756
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO75154
Background Information
  • Uniprot Id

    O75154

  • Target Species

    Human

  • Target Name

    RAB11FIP3

  • Target Full Name

    Rab11 family-interacting protein 3

  • Target Function

    Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track).

  • Target Subcellular Location

    Recycling endosome membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody.

  • Target Synonyms

    RAB11FIP3; ARFO1; KIAA0665; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3; Arfophilin-1; EF hands-containing Rab-interacting protein; Eferin; MU-MB-17.148

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