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Recombinant Human Rab5 GDP/GTP exchange factor (RABGEF1)

ACP10762

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10762 Target NameRABGEF1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-491Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UJ41
Background Information
  • Uniprot Id

    Q9UJ41

  • Target Species

    Human

  • Target Name

    RABGEF1

  • Target Full Name

    Rab5 GDP/GTP exchange factor

  • Target Function

    Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.

  • Target Subcellular Location

    Cytoplasm. Early endosome. Recycling endosome.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    RAB guanine nucleotide exchange factor (GEF) 1; Rab5 GDP/GTP exchange factor; Rab5ef; Rabaptin 5 associated exchange factor for Rab5; Rabaptin-5-associated exchange factor for Rab5; Rabex 5; Rabex-5; RABGEF 1; Rabgef1; RABX 5; RABX5; RABX5_HUMAN; RAP1; Rin 2; Rin2

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