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Recombinant Human Ran guanine nucleotide release factor (RANGRF)

ACP19025

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19025 Target NameRANGRF
Target SynonymsDKFZp686F02139; HSPC165; HSPC236; MGC110973; MOG 1; MOG1; MOG1 homolog; MOG1_HUMAN; Ran guanine nucleotide release factor; Ran-binding protein MOG1; RanGNRF; RANGRFFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-186
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9HD47
Background Information
  • Uniprot Id

    Q9HD47

  • Target Species

    Human

  • Target Name

    RANGRF

  • Target Full Name

    Ran guanine nucleotide release factor

  • Target Function

    May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics. Enhances the expression of SCN5A at the cell membrane in cardiomyocytes.

  • Target Subcellular Location

    Nucleus. Cytoplasm, perinuclear region. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Protein Families

    MOG1 family

  • Target Tissue Specificity

    Isoform 1 and isoform 2 are ubiquitously expressed. Detected in heart and brain.

  • Target Synonyms

    DKFZp686F02139; HSPC165; HSPC236; MGC110973; MOG 1; MOG1; MOG1 homolog; MOG1_HUMAN; Ran guanine nucleotide release factor; Ran-binding protein MOG1; RanGNRF; RANGRF

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