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Recombinant Human RAS guanyl-releasing protein 4 (RASGRP4)

ACP14808

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14808 Target NameRASGRP4
Target SynonymsGRP4_HUMAN; Guanyl nucleotide releasing protein 4; RAS guanyl releasing protein 4; RAS guanyl-releasing protein 4; RASGRP4FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-673
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TDF6
Background Information
  • Uniprot Id

    Q8TDF6

  • Target Species

    Human

  • Target Name

    RASGRP4

  • Target Full Name

    RAS guanyl-releasing protein 4

  • Target Function

    Functions as a cation- and diacylglycerol (DAG)-regulated nucleotide exchange factor activating Ras through the exchange of bound GDP for GTP. May function in mast cells differentiation.

  • Target Subcellular Location

    Cytoplasm. Cell membrane. Note=Recruited to membranes upon activation by DAG.

  • Target Protein Families

    RASGRP family

  • Target Tissue Specificity

    Expressed by mast cells and their progenitors (at protein level). Specifically expressed in mononuclear leukocytes. Highly expressed in myeloid cells compared to lymphoid cells. Also detected in heart, skeletal muscle, spleen, liver, placenta and lung. No

  • Target Synonyms

    GRP4_HUMAN; Guanyl nucleotide releasing protein 4; RAS guanyl releasing protein 4; RAS guanyl-releasing protein 4; RASGRP4

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