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| Cat.No | ACP13246 | Target Name | RERG |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-199 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96A58 |
|---|
Uniprot Id
Q96A58
Target Species
Human
Target Name
RERG
Target Full Name
Ras-related and estrogen-regulated growth inhibitor
Target Function
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Small GTPase superfamily, Ras family
Target Tissue Specificity
Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of
Target Synonyms
MGC15754 ; RAS like estrogen regulated growth inhibitor ; Ras related and estrogen regulated growth inhibitor ; Ras-related and estrogen-regulated growth inhibitor; Rerg; RERG_HUMAN; Weakly similar to N ras protein [H.sapiens]
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