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Recombinant Human Replication protein A 30 kDa subunit (RPA4)

ACP17880

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Specifications

Cat.No	ACP17880	Target Name	RPA4
Target Synonyms	HSU24186 ; MGC120333 ; MGC120334; p30; Replication factor A protein 4; Replication protein A 30 kDa subunit; RF A ; RF-A protein 4; RFA ; RFA4_HUMAN; RP A; RP-A p30; RPA; RPA4	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-261
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q13156

Background Information

Uniprot Id

Q13156
Target Species

Human
Target Name

RPA4
Target Full Name

Replication protein A 30 kDa subunit
Target Function

As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Target Subcellular Location

Nucleus. Note=Localizes to DNA repair foci after DNA damage.
Target Protein Families

Replication factor A protein 2 family
Target Tissue Specificity

Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

HSU24186 ; MGC120333 ; MGC120334; p30; Replication factor A protein 4; Replication protein A 30 kDa subunit; RF A ; RF-A protein 4; RFA ; RFA4_HUMAN; RP A; RP-A p30; RPA; RPA4

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Recombinant Human Replication protein A 30 kDa subunit (RPA4)

Specifications

Immunogen Information

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