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Recombinant Human Retinoschisin (RS1)

ACP02696

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP02696 Target NameRS1
Target SynonymsRetinoschisin; RS1; X-linked juvenile retinoschisis protein; XLRS1_HUMANFormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range24-224aa
Mol Weight50.0kDaProtein LengthFull Length of Mature Protein
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO15537
Background Information
  • Uniprot Id

    O15537

  • Target Species

    Human

  • Target Name

    RS1

  • Target Full Name

    Retinoschisin

  • Target Function

    Binds negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides. May play a role in cell-cell adhesion processes in the retina, via homomeric interaction between octamers present on the surface of two neighboring cells. Required for normal structure and function of the retina.

  • Target Involvement

    Retinoschisis juvenile X-linked 1 (XLRS1)

  • Target Subcellular Location

    Secreted. Cell membrane; Peripheral membrane protein; Extracellular side.

  • Target Tissue Specificity

    Restricted to the retina (at protein level). Detected in the inner segment of the photoreceptors, the inner nuclear layer, the inner plexiform layer and the ganglion cell layer (at protein level). At the macula, expressed in both the outer and inner nucle

  • Target Research Area

    Cell Adhesion

  • Target Synonyms

    Retinoschisin; RS1; X-linked juvenile retinoschisis protein; XLRS1_HUMAN

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