Home Products Recombinant Human Rho GTPase-activating protein 32 (ARHGAP32), Truncated

Recombinant Human Rho GTPase-activating protein 32 (ARHGAP32), Truncated

ACP19879

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP19879	Target Name	ARHGAP32
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	A7KAX9

Background Information

Uniprot Id

A7KAX9
Target Species

Human
Target Name

ARHGAP32
Target Full Name

Rho GTPase-activating protein 32
Target Function

GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity.
Target Subcellular Location

Cell junction, synapse, postsynaptic density. Cell projection, dendritic spine. Cytoplasm, cell cortex. Endosome membrane. Golgi apparatus membrane. Endoplasmic reticulum membrane. Membrane.
Target Protein Families

PX domain-containing GAP family
Target Tissue Specificity

Isoform 1 and isoform 2 are highly expressed in brain and testis. Isoform 1 is also expressed in other tissues such as lung, liver and spleen.
Target Synonyms

ARHGAP32; GRIT; KIAA0712; RICS; Rho GTPase-activating protein 32; Brain-specific Rho GTPase-activating protein; GAB-associated Cdc42/Rac GTPase-activating protein; GC-GAP; GTPase regulator interacting with TrkA; Rho-type GTPase-activating protein 32; Rho/Cdc42/Rac GTPase-activating protein RICS; RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; p200RhoGAP; p250GAP

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Recombinant Human Rho GTPase-activating protein 32 (ARHGAP32), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Rho GTPase-activating protein 32 (ARHGAP32), Truncated Now

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