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Recombinant Human Rho-guanine nucleotide exchange factor (RGNEF), Truncated

ACP13130

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13130 Target NameARHGEF28
Target SynonymsARHGEF28; KIAA1998; RGNEF; Rho guanine nucleotide exchange factor 28; 190 kDa guanine nucleotide exchange factor; p190-RhoGEF; p190RhoGEF; Rho guanine nucleotide exchange factorFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N1W1
Background Information
  • Uniprot Id

    Q8N1W1

  • Target Species

    Human

  • Target Name

    ARHGEF28

  • Target Full Name

    Rho guanine nucleotide exchange factor 28

  • Target Function

    Functions as a RHOA-specific guanine nucleotide exchange factor regulating signaling pathways downstream of integrins and growth factor receptors. Functions in axonal branching, synapse formation and dendritic morphogenesis. Functions also in focal adhesion formation, cell motility and B-lymphocytes activation. May regulate NEFL expression and aggregation and play a role in apoptosis.

  • Target Subcellular Location

    Cytoplasm. Cell membrane.

  • Target Synonyms

    ARHGEF28; KIAA1998; RGNEF; Rho guanine nucleotide exchange factor 28; 190 kDa guanine nucleotide exchange factor; p190-RhoGEF; p190RhoGEF; Rho guanine nucleotide exchange factor

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