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| Cat.No | ACP22627 | Target Name | RND3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-241 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P61587 |
|---|
Uniprot Id
P61587
Target Species
Human
Target Name
RND3
Target Full Name
Rho-related GTP-binding protein RhoE
Target Function
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
Target Subcellular Location
Golgi apparatus membrane; Peripheral membrane protein.
Target Protein Families
Small GTPase superfamily, Rho family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
ARHE; memB; Protein MemB; Ras homolog gene family member E; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; Rho8; RhoE; Rnd3; RND3_HUMAN; Small GTP binding protein Rho8
Target Background
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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