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Recombinant Human Ribosomal RNA processing protein 1 homolog B (RRP1B)

ACP18468

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Specifications

Cat.No	ACP18468	Target Name	RRP1B
Target Synonyms	RRP1B; KIAA0179; Ribosomal RNA processing protein 1 homolog B; RRP1-like protein B	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-758
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q14684

Background Information

Uniprot Id

Q14684
Target Species

Human
Target Name

RRP1B
Target Full Name

Ribosomal RNA processing protein 1 homolog B
Target Function

Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1. Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus. Involved in regulation of mRNA splicing. Inhibits SIPA1 GTPase activity. Involved in regulating expression of extracellular matrix genes. Associates with chromatin and may play a role in modulating chromatin structure.; (Microbial infection) Following influenza A virus (IAV) infection, promotes viral mRNA transcription by facilitating the binding of IAV RNA-directed RNA polymerase to capped mRNA
Target Subcellular Location

Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome.; Nucleus, nucleoplasm.
Target Protein Families

RRP1 family
Target Synonyms

RRP1B; KIAA0179; Ribosomal RNA processing protein 1 homolog B; RRP1-like protein B

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Recombinant Human Ribosomal RNA processing protein 1 homolog B (RRP1B)

Specifications

Immunogen Information

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