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Recombinant Human RILP-like protein 1 (RILPL1)

ACP17276

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17276 Target NameRILPL1
Target SynonymsGOSPEL; MGC105128 ; MGC99793; Rab interacting lysosomal protein like 1; Rab-interacting lysosomal-like protein 1; RILP like protein 1; RILP-like protein 1; RILPL 1; rilpl1; RIPL1_HUMAN; RLP1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-403
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5EBL4
Background Information
  • Uniprot Id

    Q5EBL4

  • Target Species

    Human

  • Target Name

    RILPL1

  • Target Full Name

    RILP-like protein 1

  • Target Function

    Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution. Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis.

  • Target Subcellular Location

    Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.

  • Target Protein Families

    RILPL family

  • Target Tissue Specificity

    Widely expressed. Expressed at lower level in liver and kidney.

  • Target Synonyms

    GOSPEL; MGC105128 ; MGC99793; Rab interacting lysosomal protein like 1; Rab-interacting lysosomal-like protein 1; RILP like protein 1; RILP-like protein 1; RILPL 1; rilpl1; RIPL1_HUMAN; RLP1

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