Recombinant Human RING finger and transmembrane domain-containing protein 1 (RNFT1), Truncated

ACP08313

Number

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Specifications

Cat.No	ACP08313	Target Name	RNFT1
Target Synonyms	RNFT1; PTD016; E3 ubiquitin-protein ligase RNFT1; Protein PTD016; RING finger and transmembrane domain-containing protein 1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q5M7Z0

Background Information

Uniprot Id

Q5M7Z0
Target Species

Human
Target Name

RNFT1
Target Full Name

E3 ubiquitin-protein ligase RNFT1
Target Function

E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.
Target Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Tissue Specificity

Expressed at highest levels in testis, lower levels in heart, liver, lung, and kidney. Not detected in brain, ovary, and uterus. Down-regulated in testis from patients with maturation arrest (MA) or Sertoli cell-only syndrome (SCOS). Ubiquitously expresse
Target Synonyms

RNFT1; PTD016; E3 ubiquitin-protein ligase RNFT1; Protein PTD016; RING finger and transmembrane domain-containing protein 1

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Recombinant Human RING finger and transmembrane domain-containing protein 1 (RNFT1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human RING finger and transmembrane domain-containing protein 1 (RNFT1), Truncated Now

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