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| Cat.No | ACP19581 | Target Name | RNF165 |
|---|---|---|---|
| Target Synonyms | RNF165; E3 ubiquitin-protein ligase RNF165; EC 2.3.2.27; RING finger protein 165 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-346 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZSG1 |
|---|
Uniprot Id
Q6ZSG1
Target Species
Human
Target Name
ARK2C
Target Full Name
E3 ubiquitin-protein ligase ARK2C
Target Function
E3 ubiquitin-protein ligase that acts as a regulator of motor axon elongation. Required for efficient motor axon extension in the dorsal forelimb by enhancing the transcriptional responses of the SMAD1/SMAD5/SMAD8 effectors, which are activated downstream of BMP. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL.
Target Subcellular Location
Nucleus.
Target Protein Families
Arkadia family
Target Synonyms
RNF165; E3 ubiquitin-protein ligase RNF165; EC 2.3.2.27; RING finger protein 165
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