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Recombinant Human RING finger protein 165 (RNF165)

ACP19581

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19581 Target NameRNF165
Target SynonymsRNF165; E3 ubiquitin-protein ligase RNF165; EC 2.3.2.27; RING finger protein 165FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-346
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6ZSG1
Background Information
  • Uniprot Id

    Q6ZSG1

  • Target Species

    Human

  • Target Name

    ARK2C

  • Target Full Name

    E3 ubiquitin-protein ligase ARK2C

  • Target Function

    E3 ubiquitin-protein ligase that acts as a regulator of motor axon elongation. Required for efficient motor axon extension in the dorsal forelimb by enhancing the transcriptional responses of the SMAD1/SMAD5/SMAD8 effectors, which are activated downstream of BMP. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Arkadia family

  • Target Synonyms

    RNF165; E3 ubiquitin-protein ligase RNF165; EC 2.3.2.27; RING finger protein 165

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