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| Cat.No | ACP19244 | Target Name | RNF166 |
|---|---|---|---|
| Target Synonyms | 1110031E24Rik; AW555115; MGC14381; MGC2647; RING finger protein 166; RN166_HUMAN; RNF 166; RNF166; Zfp313l; Zinc finger protein 228; Zinc finger protein 313 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-237 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96A37 |
|---|
Uniprot Id
Q96A37
Target Species
Human
Target Name
RNF166
Target Full Name
E3 ubiquitin-protein ligase RNF166
Target Function
E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Plays also a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.
Target Subcellular Location
Cytoplasm.
Target Synonyms
1110031E24Rik; AW555115; MGC14381; MGC2647; RING finger protein 166; RN166_HUMAN; RNF 166; RNF166; Zfp313l; Zinc finger protein 228; Zinc finger protein 313
Target Background
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm.
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