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| Cat.No | ACP19501 | Target Name | RTTN |
|---|---|---|---|
| Target Synonyms | DKFZP434G145; Rotatin; Rttn; RTTN_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86VV8 |
|---|
Uniprot Id
Q86VV8
Target Species
Human
Target Name
RTTN
Target Full Name
Rotatin
Target Function
Involved in the genetic cascade that governs left-right specification. Plays a role in the maintenance of a normal ciliary structure. Required for correct asymmetric expression of NODAL, LEFTY and PITX2.
Target Involvement
Microcephaly, short stature, and polymicrogyria with or without seizures (MSSP)
Target Subcellular Location
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with the basal bodies at the primary cilium.
Target Synonyms
DKFZP434G145; Rotatin; Rttn; RTTN_HUMAN
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