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Recombinant Human Rotatin (RTTN), Truncated

ACP19501

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19501 Target NameRTTN
Target SynonymsDKFZP434G145; Rotatin; Rttn; RTTN_HUMANFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ86VV8
Background Information
  • Uniprot Id

    Q86VV8

  • Target Species

    Human

  • Target Name

    RTTN

  • Target Full Name

    Rotatin

  • Target Function

    Involved in the genetic cascade that governs left-right specification. Plays a role in the maintenance of a normal ciliary structure. Required for correct asymmetric expression of NODAL, LEFTY and PITX2.

  • Target Involvement

    Microcephaly, short stature, and polymicrogyria with or without seizures (MSSP)

  • Target Subcellular Location

    Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with the basal bodies at the primary cilium.

  • Target Synonyms

    DKFZP434G145; Rotatin; Rttn; RTTN_HUMAN

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