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| Cat.No | ACP11402 | Target Name | SACS |
|---|---|---|---|
| Target Synonyms | DnaJ homolog subfamily C member 29; DNAJC29; SACS; SACS_HUMAN; Sacsin; Spastic ataxia of Charlevoix-Saguenay | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NZJ4 |
|---|
Uniprot Id
Q9NZJ4
Target Species
Human
Target Name
SACS
Target Full Name
Sacsin
Target Function
Co-chaperone which acts as a regulator of the Hsp70 chaperone machinery and may be involved in the processing of other ataxia-linked proteins.
Target Involvement
Spastic ataxia Charlevoix-Saguenay type (SACS)
Target Subcellular Location
Cytoplasm. Note=Predominantly cytoplasmic, a small portion is present in the nucleus and also shows a partial mitochondrial overlap with the mitochondrial marker Hsp60.
Target Tissue Specificity
Highly expressed in the central nervous system. Also found in skeletal muscle and at low levels in pancreas.
Target Synonyms
DnaJ homolog subfamily C member 29; DNAJC29; SACS; SACS_HUMAN; Sacsin; Spastic ataxia of Charlevoix-Saguenay
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