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Recombinant Human Scaffold attachment factor B2 (SAFB2), Truncated

ACP18769

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18769 Target NameSAFB2
Target SynonymsDKFZP779C1727; HAP; HET; hsp27 ere tata binding; KIAA0138 ; SAF B; SAF B2 ; SAF-B2; SAFB; SAFB1; SAFB2; SAFB2_HUMAN; Scaffold attachment factor B2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ14151
Background Information
  • Uniprot Id

    Q14151

  • Target Species

    Human

  • Target Name

    SAFB2

  • Target Full Name

    Scaffold attachment factor B2

  • Target Function

    Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Tissue Specificity

    Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.

  • Target Synonyms

    DKFZP779C1727; HAP; HET; hsp27 ere tata binding; KIAA0138 ; SAF B; SAF B2 ; SAF-B2; SAFB; SAFB1; SAFB2; SAFB2_HUMAN; Scaffold attachment factor B2

  • Target Background

    The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes.

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