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Recombinant Human Secreted frizzled-related protein 2 (SFRP2)

ACP19208

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19208 Target NameSFRP2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range25-295Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ96HF1
Background Information
  • Uniprot Id

    Q96HF1

  • Target Species

    Human

  • Target Name

    SFRP2

  • Target Full Name

    Secreted frizzled-related protein 2

  • Target Function

    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Secreted frizzled-related protein (sFRP) family

  • Target Tissue Specificity

    Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.

  • Target Research Area

    Cancer

  • Target Synonyms

    AI851596; Frizzled related protein 2; FRP 2; FRP-2; FRP2; MGC128911; MGC153618; MGC53344; SARP 1; SARP-1; SARP1; SDF 5; SDF5; Secreted apoptosis related protein 1; Secreted apoptosis-related protein 1; Secreted frizzled related protein 2; Secreted frizzled-related protein 2; sFRP 2; sFRP-2; SFRP2; Sfrp2 protein ; SFRP2_HUMAN

  • Target Background

    This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.

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