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| Cat.No | ACP13578 | Target Name | SCG3 |
|---|---|---|---|
| Target Synonyms | 1B1075; AI385542; Chgd; SCG3; SCG3_HUMAN; Secretogranin III; Secretogranin-3; SGCG; SgIII | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 20-468 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WXD2 |
|---|
Uniprot Id
Q8WXD2
Target Species
Human
Target Name
SCG3
Target Full Name
Secretogranin-3
Target Function
Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted.
Target Tissue Specificity
Expressed in brain, heart, kidney, liver and skeletal muscle.
Target Synonyms
1B1075; AI385542; Chgd; SCG3; SCG3_HUMAN; Secretogranin III; Secretogranin-3; SGCG; SgIII
Target Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.
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