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| Cat.No | ACP01839 | Target Name | SEMA3B |
|---|---|---|---|
| Target Synonyms | Sema A(V) Semaphorin-V | Form | Liquid or Lyophilized powder |
| Expression System | Baculovirus | Expression Range | 25-749aa |
| Mol Weight | 84.8 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13214 |
|---|
Uniprot Id
Q13214
Target Species
Human
Target Name
SEMA3B
Target Full Name
Semaphorin-3B
Target Function
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Target Subcellular Location
Secreted. Endoplasmic reticulum. Note=Accumulates in the endoplasmic reticulum.
Target Protein Families
Semaphorin family
Target Tissue Specificity
Expressed abundantly but differentially in a variety of neural and nonneural tissues.
Target Research Area
Cancer
Target Synonyms
SEM3B_HUMAN; Sema A(V); Sema V; Sema3b; Semaphorin V; Semaphorin-3B; Semaphorin-V
Target Background
The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants.
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