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| Cat.No | ACP06270 | Target Name | SERINC5 |
|---|---|---|---|
| Target Synonyms | C5orf12; SERC5_HUMAN; SERINC5; Serine incorporator 5; TPO1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86VE9 |
|---|
Uniprot Id
Q86VE9
Target Species
Human
Target Name
SERINC5
Target Full Name
Serine incorporator 5
Target Function
Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm. Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.; Cytoplasm, perinuclear region.
Target Protein Families
TDE1 family
Target Tissue Specificity
Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain.
Target Synonyms
C5orf12; SERC5_HUMAN; SERINC5; Serine incorporator 5; TPO1
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