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| Cat.No | ACP03417 | Target Name | STK16 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-305aa | Mol Weight | 61.5kDa |
| Protein Length | Full length | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75716 |
|---|
Uniprot Id
O75716
Target Species
Human
Target Name
STK16
Target Full Name
Serine/threonine-protein kinase 16
Target Function
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Target Subcellular Location
Cytoplasm, perinuclear region. Membrane; Lipid-anchor.
Target Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Target Tissue Specificity
Ubiquitously expressed at very low levels.
Target Research Area
Signal Transduction
Target Synonyms
EDPK; F52; FLJ39635; hPSK; KRCT; MGC16211; MPSK; MPSK1; Myristoylated and palmitoylated serine/threonine protein kinase; Myristoylated and palmitoylated serine/threonine-protein kinase; PKL12 ; Protein kinase expressed in day 12 fetal liver ; Protein kinase Krct; Protein kinase PKL12; Serine/threonine kinase 16 ; Serine/threonine protein kinase 16; Serine/threonine-protein kinase 16; Stk16; STK16_HUMAN; TGF beta stimulated factor 1; TGF-beta-stimulated factor 1; TGFB stimulated factor 1; Transforming growth factor beta stimulated factor 1; TSF-1; TSF1; Tyrosine protein kinase STK16
Target Background
Predicted to enable protein serine/threonine kinase activity. Involved in protein autophosphorylation. Located in cytosol; nucleoplasm; and plasma membrane.
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