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Recombinant Human Serine/threonine-protein kinase haspin (GSG2)

ACP14794

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14794 Target NameHASPIN
Target Synonymsgerm cell associated 2; Germ cell-specific gene 2 protein; GSG2; H-haspin; Haploid germ cell-specific nuclear protein kinase; HASP_HUMAN; Serine/threonine-protein kinase haspinFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-798
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TF76
Background Information
  • Uniprot Id

    Q8TF76

  • Target Species

    Human

  • Target Name

    HASPIN

  • Target Full Name

    Serine/threonine-protein kinase haspin

  • Target Function

    Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.

  • Target Subcellular Location

    Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis.

  • Target Protein Families

    Protein kinase superfamily, Ser/Thr protein kinase family, Haspin subfamily

  • Target Tissue Specificity

    Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferatin

  • Target Synonyms

    germ cell associated 2; Germ cell-specific gene 2 protein; GSG2; H-haspin; Haploid germ cell-specific nuclear protein kinase; HASP_HUMAN; Serine/threonine-protein kinase haspin

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