Recombinant Human Serpin H1 (SERPINH1)

Cat.No	ACP00844	Target Name	Serpinh1
Target Synonyms	(47 kDa heat shock protein)(Arsenic-transactivated protein 3)(AsTP3)(Cell proliferation-inducing gene 14 protein)(Collagen-binding protein)(Colligin)(Rheumatoid arthritis-related antigen RA-A47)	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	19-418aa
Mol Weight	50.5 kDa	Protein Length	Full Length of Mature Protein
Purity	Greater than 85% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP00844

Target Name

Serpinh1

Target Synonyms

(47 kDa heat shock protein)(Arsenic-transactivated protein 3)(AsTP3)(Cell proliferation-inducing gene 14 protein)(Collagen-binding protein)(Colligin)(Rheumatoid arthritis-related antigen RA-A47)

Form

Liquid or Lyophilized powder

Expression System

E.coli

Expression Range

19-418aa

Mol Weight

50.5 kDa

Protein Length

Full Length of Mature Protein

Purity

Greater than 85% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P50454

Background Information

Uniprot Id

P50454
Target Species

Human
Target Name

SERPINH1
Target Full Name

Serpin H1
Target Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
Target Involvement

Osteogenesis imperfecta 10 (OI10)
Target Subcellular Location

Endoplasmic reticulum lumen.
Target Protein Families

Serpin family
Target Research Area

Signal Transduction
Target Synonyms

47 kDa heat shock protein; 47 kDa heat shock protein precursor; Arsenic transactivated protein 3; Arsenic-transactivated protein 3; AsTP 3; AsTP3; CBP 1; CBP 2; CBP1; CBP2; Cell proliferation-inducing gene 14 protein; Collagen binding protein 1; Collagen binding protein 2; Collagen binding protein; Collagen-binding protein 2; Collagen-binding protein; Colligen; Colligin 1; Colligin 2; Colligin; colligin-1; colligin-2; gp46; Heat shock protein 47; Heat-shock protein 47; HGNC 1547; Hsp 47; J6; OI10; PIG 14; PIG14; PPROM; Proliferation inducing gene 14; Proliferation inducing gene 14 protein; RA A47; RA-A47; Rheumatoid arthritis antigen A 47; rheumatoid arthritis antigen A-47; Rheumatoid arthritis related antigen RA A47; Rheumatoid arthritis-related antigen RA-A47; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2); Serine or cysteine proteinase inhibitor clade H member 1; Serine or cysteine proteinase inhibitor clade H member 2; SERPH_HUMAN; Serpin H1; Serpin peptidase inhibitor clade H member 1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); Serpin peptidase inhibitor, clade H, member 1; SERPINH1; SERPINH2
Target Background

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Recombinant Human Serpin H1 (SERPINH1)

Specifications

Immunogen Information

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